Abstract: Objective To investigate the clinical characteristics of pulmonary tuberculosis complicated with Acinetobacter baumannii (Ab) infection, and to analyze Ab resistance to commonly used antibiotics. Methods One hundred and twenty-nine cases with pulmonary tuberculosis complicated with Ab infection were retrospectively analyzed from January 2009 to December 2012. The sputum specimens were inoculated in blood agar, chocolate agar and MacConkey agar. The susceptibility tests of 18 drugs including cefoperazone shubatan and imipenem were performed by VITEK-32 automatic microorganism analysis system.  Results One hundred and thirty-eight Ab strains were isolated from 129 patients, 25 strains (18.1%) in 2009, 32 strains (23.2%) in 2010, 39 strains (28.3%) in 2011, and 42 strains (30.4%) in 2012. Ab resistance to commonly used antibiotics increased year by year. The rates of Ab resistance to cefoperazone shubatan and imipenem were respectively 4.0% (1/25) and 12.0% (3/25) in 2009，9.4% (3/32) and 18.8% (6/32) in 2010，25.6% (10/39) and 28.2% (11/39) in 2011，50.0% (21/42) and 45.2% (19/42) in 2012. Conclusion Compared with 2009, the ratio of tuberculosis complicated with Ab infection increased significantly in 2012. Ab resistance to commonly used antibiotics increased year by year.

Key words: Tuberculosis, pulmonary/complications, Acinetobacter baumannii, Acinetobacter infections, Drug resistance, bacterial, Microbial sensitivity tests